Hyperthyroidism with increased factor VIII procoagulant protein as a predisposing factor for cerebral venous thrombosis
نویسندگان
چکیده
منابع مشابه
Recurrent Cerebral Venous Thrombosis Associated with Elevated Factor VIII
Cerebral venous thrombosis (CVT) rarely recurs, and the factors associated with a recurrence remain unclear. Recently, however, elevated plasma coagulation factor VIII has been considered a factor related to recurrent venous thromboembolism. Here we report a patient who had recurrent CVT associated with significantly elevated levels of factor VIII despite the chronic use of an antiplatelet agen...
متن کاملCerebral Sinus and Venous Thrombosis Associated with von Willebrand Factor, Independently of Factor VIII
BACKGROUND AND PURPOSE Previous studies have linked procoagulant factor VIII (F VIII) to an increased risk of venous thrombosis, whereas the relation between plasma von Willebrand factor (VWF) and venous thrombosis remains poorly understood. Elevated VWF levels are frequently found in patients with cerebral sinus and venous thrombosis (CSVT), always in association with high F VIII levels. We de...
متن کاملElevated factor VIII: an unfamiliar risk factor for cerebral venous thrombosis.
An elevated factor VIII level has been shown to be an independent risk factor for venous thrombosis. However, physicians screen for this factor far less frequently than they screen for other coagulopathies. The causes of increased factor VIII levels are likely a combination of genetic and acquired variables. The authors describe a case of a healthy 48-year-old woman found to have a cerebral ven...
متن کاملApparent molecular weight of purified human factor VIII procoagulant protein compared with purified and plasma factor VIII procoagulant protein antigen.
We have compared apparent molecular weights of purified factor VIII procoagulant protein (VIII:C) and VIII:C antigen (VIII:CAg) by two different NaDodSO4 gel electrophoretic techniques. In a discontinuous NaDodSO4-7.5% polyacrylamide system, reduced and unreduced VIII:C, purified from commercial factor VIII concentrates by a monoclonal antibody immunoadsorption technique, showed a major doublet...
متن کاملCerebral Venous Thrombosis and Hyperthyroidism
CVT has the best prognosis at a young age without severe neurological deficits, such as hemiparesis, epileptic seizures and coma, or other co-morbidity such as cancer and serious infection [3]. A prospective multi-center study showed that 75% of patients with CVT were women with a mean age of 34 years and the best prognosis was found for women with risk factors like hormonal contraception, preg...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2002
ISSN: 0022-3050
DOI: 10.1136/jnnp.73.4.458